ASTERIX version 1

  • Research type

    Research Study

  • Full title

    ASTERIX: Adaptive Stratification of COVID19 to facilitate Endotype-directed Intervention Studies

  • IRAS ID

    283989

  • Contact name

    Kevin Blyth

  • Contact email

    kevin.blyth@ggc.scot.nhs.uk

  • Sponsor organisation

    R&I, NHS Greater Glasgow and Clyde, Glasgow

  • Clinicaltrials.gov Identifier

    To be confirmed, ISRCTN; 20/WS/0077, REC Reference

  • Duration of Study in the UK

    1 years, 0 months, days

  • Research summary

    Research Summary:
    The new coronavirus19 disease is a rapidly emerging global health threat and, as yet, does not have effective therapies for severe disease. The disease can affect people very differently and we wish to look at subtypes using biological signatures to help us design clinical trials that have the highest chance of success. ASTERIX is an observational study that will collect surplus samples (blood, respiratory secretions and urine) and data on COVID patients admitted to hospital. Models will be produced that identify patients at the highest risk of adverse outcomes and how these might be addressed in future trials that our group plan to design.

    Lay Summary of results:

    The data is currently being analysed for the cohort of 4088 patients.

  • REC name

    West of Scotland REC 5

  • REC reference

    20/WS/0077

  • Date of REC Opinion

    21 May 2020

  • REC opinion

    Favourable Opinion