Association between PROMs and frailty in colorectal cancer patients
Research type
Research Study
Full title
Investigating the relationship between patient reported outcome measures and preoperative frailty in patients with operable, no-palliative colorectal cancer
IRAS ID
263233
Contact name
Reema Ayyash
Contact email
Sponsor organisation
South Tees Hospitals NHS FT
Duration of Study in the UK
1 years, 10 months, 2 days
Research summary
Background\nFrailty is a condition often associated with getting older. People who are frail are at a greater risk of weight loss, low mood, reduced muscle strength and slowing down when doing everyday tasks. They tend to be more susceptible to sudden deterioration in their health, which is often brought about by stressful events such as surgery. We know that frail individuals are more likely to suffer complications after surgery. However, there is little information about how different levels of frailty affects recovery after bowel cancer surgery. \n\nMethods\nThis is a multi-centre observational study, conducted across three hospitals: Middlesbrough, North Tees and York. All patients with operable, non palliative colorectal cancer aged over 65 will be sent a patient information leaflet. Further information will be provided at the preassessment clinic visit, and interested patients asked to sign a consent form. In patients with memory problems, consent will be obtained from their personal consultee. \nThe researcher will complete two questionnaires about frailty and one short physical task to assess mobility. The researcher will then assist the participant or their carer in completing two short questionnaires about their current quality of life (QoL) and functional abilities. Two questionnaires will be repeated by the patient at home approximately at 6 and 12-weeks, with all 4 questionnaires repeated approximately at the 12-week surgical follow up clinic. \nThe researcher will review the participant’s medical notes and record information about their cancer and treatment. \nA participant focus groups will take place at mid-point and end of the study period to feedback results and discuss about how to use the information for future patients. \n\nExpected outcomes and implications\nThe study will help define the prevalence of frailty in older colorectal cancer patients and understand how frailty impacts on patient reported outcome measures.
REC name
Yorkshire & The Humber - Bradford Leeds Research Ethics Committee
REC reference
19/YH/0194
Date of REC Opinion
4 Sep 2019
REC opinion
Further Information Favourable Opinion