Assessment of rubella titres in COVID-19 patients [COVID-19]

• Research type

  Research Study

• Full title

  Assessment of rubella titres in COVID-19 patients

• IRAS ID

  282308

• Contact name

  Adam Young

• Contact email

  ay276@cam.ac.uk

• Sponsor organisation

  Cambridge University

• Duration of Study in the UK

  0 years, 3 months, 1 days

• Research summary

  The striking feature of COVID-19 is that it ravages the elderly population so violently, yet the paediatric populations in many reports escape with mild, if any, symptoms. We have found sequence homology in the viral capsid of Rubella virus with SARS-CoV2. The 3D viral model of SARS-CoV2 has identified that the homologous sequence is used to bind to the cells and as a result we propose that Rubella anti-bodies would be potentially protective in COVID-19 infection. \n\nWe propose to use the biochemistry samples of COVID-19 patients sent to the laboratory to check for Rubella Immunoglobulin titres and correlate with burden of disease.

• REC name

  Yorkshire & The Humber - Leeds West Research Ethics Committee

• REC reference

  20/YH/0125

• Date of REC Opinion

  30 Mar 2020

• REC opinion

  Favourable Opinion