Assessment of MBL deficiency in pancreatic islet auto-transplantation
Research type
Research Study
Full title
Assessment of mannose-binding lectin-dependent pathway deficiency in the pancreatic islet auto-transplantation patient.
IRAS ID
146165
Contact name
Ashley Dennison
Contact email
Sponsor organisation
University Hospitals of Leicester NHS Trust
Research summary
We would like to take a research blood sample from patients who have had their pancreas removed and have received an islet auto-transplantation. We would like to investigate the complement system; this system plays a major role in inflammation and the body's immune response. Approximately 10% of the population are deficient in the MBL pathway. Taking a blood sample will allow us to measure different people's complement response - this may lead to a test predicting how well different people recover from this type of surgery.
REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
14/NE/0075
Date of REC Opinion
5 Mar 2014
REC opinion
Favourable Opinion