Assessing the agreement between tonometers
Research type
Research Study
Full title
Prospective observational study to investigate the agreement in intraocular pressure measurement between various tonometers currently employed in clinical practice.
IRAS ID
86094
Contact name
Maged Nessim
Contact email
Sponsor organisation
Sandwell & West Birmingham Hospitals NHS Trust
Research summary
This is a prospective observational study which aims to compare the measurement of intraocular pressure (the pressure within the eye) (IOP) between the gold standard of 50 years the Goldmann applanation tonometry (GAT) and other tonometers currently employed in clinical practice. These include an electronic tonometer (Tonopen), a rebound tonometer (ICare) and non contact tonometers (Ocular Response Analyzer and Corvis ST). These instruments work in different manners and may be affected by eye structure in different ways and hence produce different measured IOP. IOP is an important measure in all aspect of eye care and could be considered the counterpart of blood pressure for general health.
All subjects will be patients attending the eye department for management of their ocular disease. The subjects will undergo IOP measurement using all the tonometers in random order on a single visit. One of the measures of IOP would have been required for general clinical care in any case as this is a routine measurement for all patients.
In our analysis we will include healthy individuals, patients affected by glaucoma, ocular hypertension, corneal diseases, cataracts and other ocular pathologies. We aim to recruit 365 patients as per statistical advice.
There will be no follow up needed in this study.
REC name
West Midlands - Solihull Research Ethics Committee
REC reference
13/WM/0343
Date of REC Opinion
3 Oct 2013
REC opinion
Further Information Favourable Opinion