ASPIRE
Research type
Research Study
Full title
Aspirin resistance among pregnant women at risk of preeclampsia
IRAS ID
123712
Contact name
Vijay Kunadian
Contact email
Sponsor organisation
Newcastle Upon Tyne NHS foundation Trust
Research summary
Cardiovascular diseases remain the leading cause of death particularly among younger women. Diseases such as preeclampsia (PE) and gestational diabetes are unique among women that lead to poor outcomes including the occurrence of myocardial infarction and death in the future. Strategies to prevent such pregnancy related diseases are required to improve clinical outcomes among women. The current study is designed to determine the benefit of the use of low dose aspirin among women at risk of preeclampsia. Given not all patients respond to aspirin therapy adequately in terms of platelet inhibition, the present study will determine all patients’ response to aspirin therapy using specialised platelet function assays such as Verify Now and serum thromboxane B2 levels.
REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
13/NE/0106
Date of REC Opinion
30 May 2013
REC opinion
Further Information Favourable Opinion