Anti-psychotics and global coagulation assays
Research type
Research Study
Full title
Can global coagulation assays detect an increase in the prothrombotic state following commencement of antipsychotic therapy – a pilot study
IRAS ID
133034
Contact name
Roopen Arya
Contact email
Sponsor organisation
King's College Hospital
Research summary
Over the last 50 years, published information suggests that psychiatric patients are at an increased risk of developing blood clots. It is not clear why this may be the case. Some experts have hypothesised that the increased risk may be related to decreased mobility observed in this population, whilst some groups believe the increased risk is related to acute psychosis. Other research groups have suggested that it may be related the anti-psychotic drug therapy prescribed - whereby its the drugs prescribed which increase the risk. This study aims to see if global coagulation assays can detect a change in the clotting ’potential’ of blood in patients newly commenced on anti-psychotic drug therapy within the dementia patient population.
REC name
London - Camberwell St Giles Research Ethics Committee
REC reference
13/LO/1016
Date of REC Opinion
4 Sep 2013
REC opinion
Further Information Favourable Opinion