Anti-inflammatory supplement to reduce immune ageing
Research type
Research Study
Full title
An uncontrolled open label trial of a nutritional supplement to reduce measures of biological and immune ageing and improve physical function and quality of life in healthy older people
IRAS ID
308774
Contact name
Thomas Jackson
Contact email
Sponsor organisation
University of Birmingham
Duration of Study in the UK
1 years, 6 months, 1 days
Research summary
The number of people aged over 60 in the UK reached 15.5 million (23% of the population) in 2020 and their numbers continue to increase. Although more people are living for longer, they aren’t necessarily enjoying good health in their old age. Changes within the immune system with advancing age, specifically increased inflammation, are known to be related with a number of diseases which predominantly affect older people, such as heart disease, osteoporosis and dementia. The amount of inflammation in the blood has been shown to indicate how “aged” the immune system is and even how aged a person is overall (called their biological age).
Several food components (nutrients) can reduce inflammation and may reduce the degree of ageing of the immune system and have broad health benefits. However, these nutrients have not been tested in combination to see if their effects are even better.
We aim to test the effect of a nutritional supplement, developed by the company Bayer, which contains eight different nutrients that have been separately shown to reduce inflammation or improve immune function. We will measure inflammation and also whether the supplement improves physical function, quality of life and biological age.REC name
London - Bromley Research Ethics Committee
REC reference
22/PR/0698
Date of REC Opinion
22 Jun 2022
REC opinion
Favourable Opinion