Andrographis Paniculata for Acute Respiratory Tract Infections

• Research type

  Research Study

• Full title

  A double blind, randomised, placebo controlled, feasibility trial evaluating the possibility of delivering Andrographis paniculata (Immunographis) as a treatment of adults with Acute Respiratory Tract Infections (ARTIs)

• IRAS ID

  208314

• Contact name

  Michael Moore

• Contact email

  mvm198@soton.ac.uk

• Sponsor organisation

  University of Southampton

• Duration of Study in the UK

  1 years, 0 months, 0 days

• Research summary

  Acute respiratory infections (such as cough, sore throat and sinusitis) are common and therefore distressing and costly both for individuals and the NHS. Antibiotics have limited benefits and have side effects.

  A herbal medicine called Andrographis Paniculata is a promising candidate to treat acute respiratory tract infections. In a systematic review of randomised controlled trials Andrographis performed better than placebo after 5 days
  We propose to evaluate the feasibility of using Andrographis capsules in adults who visit their GP with an acute respiratory tract infection symptom and where the GP thinks the symptoms are caused by an infection (bacterial or viral) but NOT pneumonia. The doctor will be able to prescribe antibiotics if needed either taken immediately or delayed for a few days.

• REC name

  South Central - Hampshire B Research Ethics Committee

• REC reference

  18/SC/0447

• Date of REC Opinion

  19 Nov 2018

• REC opinion

  Further Information Favourable Opinion