Analysis of umbilical cord tissue from the ALSPAC study

  • Research type

    Research Study

  • Full title

    Analysing prenatal exposure against health outcomes using umbilical cord samples from participants of the Avon Longitudinal Study of Parents and Children.

  • IRAS ID

    232294

  • Contact name

    Alix Groom

  • Contact email

    alix.groom@bristol.ac.uk

  • Sponsor organisation

    University of Bristol

  • Duration of Study in the UK

    10 years, 0 months, 1 days

  • Research summary

    The proposal is for using biological material obtained for the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort. Initially recruited into the study were pregnant women between 1991 and 1992. The children arising from the pregnancies and their family members have been followed up since that time and an
    extensive amount of biological material and data is available for the study.

    This proposal is for the analysis of umbilical cord tissue which was donated to ALSPAC following the birth of the participants. The cord can be used to identify prenatal exposure of the offspring to various compounds such as metals. Exposures can then be analysed against outcomes of the participants such as their health.

  • REC name

    East of England - Cambridge Central Research Ethics Committee

  • REC reference

    17/EE/0365

  • Date of REC Opinion

    8 Sep 2017

  • REC opinion

    Unfavourable Opinion