Analysis of Graves disease using microfluidics (Version 1)

  • Research type

    Research Study

  • Full title

    The effect of corticosteroids on the release of immune modulating factors from Graves’ disease tissue maintained using microfluidic culture.

  • IRAS ID

    216622

  • Contact name

    Richard James England

  • Contact email

    james.england@hey.nhs.uk

  • Sponsor organisation

    Hull and East Yorkshire NHS Trust

  • Duration of Study in the UK

    0 years, 6 months, 1 days

  • Research summary

    A miniaturised device has been developed by the University of Hull to keep whole pieces of tissue viable and functional for up to 8 days. The aim of this research is to apply the device to a thyroid condition called Graves' disease, which is characterised by the immune system causing the thyroid gland to malfunction. This will allow us to study the biology of Graves' disease and the effect of steroids on Graves' disease, whilst the tissue is preserved outside the body.

  • REC name

    London - Hampstead Research Ethics Committee

  • REC reference

    17/LO/0209

  • Date of REC Opinion

    31 Jan 2017

  • REC opinion

    Favourable Opinion