An Online Psychological Intervention for Adults with HAE v.1

  • Research type

    Research Study

  • Full title

    An Online Acceptance and Commitment Therapy Intervention for Adults with Hereditary Angioedema: A Feasibility Study

  • IRAS ID

    339786

  • Contact name

    Rachel McGranaghan

  • Contact email

    rm02015@surrey.ac.uk

  • Sponsor organisation

    University of Surrey, Head of Assurance, RII

  • Duration of Study in the UK

    1 years, 1 months, 2 days

  • Research summary

    Hereditary Angioedema (HAE) is a rare and potentially life-threatening disorder characterised by recurrent episodes of severe swelling, most commonly in the limbs, face, intestinal tract and airway. From the limited research focusing on the lived experiences of adults with HAE, individuals report worries about future attacks and disruption to their life, as well as symptoms of anxiety and depression. Literature also suggests that increased levels of stress may be a contributing factor to triggers of oedema (swelling) attacks. It is well established that a variety of long-term conditions are associated with an increased risk of psychological problems. Acceptance and Commitment Therapy (ACT) is a psychological intervention that encourages the acceptance of negative thoughts, feelings and symptoms through skills such as mindfulness, cognitive defusion, and setting value-based goals, with aims to increase psychological flexibility. ACT is increasingly being utilised in the management of a wide range of long-term conditions and has been shown to improve quality of life and reduce psychological distress in these populations. To our knowledge, there is currently no psychological intervention specifically adapted for individuals living with HAE. This proposed study aims to evaluate the suitability and feasibility of a two-week online ACT intervention designed to improve psychological flexibility and values-based behaviours in adults with HAE.

  • REC name

    West Midlands - Black Country Research Ethics Committee

  • REC reference

    24/WM/0162

  • Date of REC Opinion

    5 Dec 2024

  • REC opinion

    Further Information Favourable Opinion