Alzheimer's Disease Genetics Scotland
Research type
Research Study
Full title
Further defining the genetic architecture of Alzheimer's disease
IRAS ID
205452
Contact name
Julie Williams
Contact email
Sponsor organisation
Cardiff University
Duration of Study in the UK
0 years, 10 months, 3 days
Research summary
Alzheimer’s disease is a common debilitating disorder, which affects individuals, families and communities. Just under half a million people have Alzheimer’s disease (AD) in the UK with an estimated cost to the economy of £24 billion per year. It is also estimated that the number of people with AD will double in the next generation. It is vital we understand what causes this disease and develop therapies to prevent, delay and treat it. Finding genes which affect the development of AD is an important means of pinpointing processes that are going wrong and contributing to the death of brain cells, which characterises this disease and underlies the symptoms of memory loss and general cognitive degeneration.
This research is focused on understanding more about how genes are involved in the cause and progression of early-onset Alzheimer’s disease (sometimes called young-onset Alzheimer’s disease). We are inviting individuals who first experienced the onset of symptoms of Alzheimer’s disease before the age of 70 to help with this research. Participants can be of any age currently.
This is an observational study that involves a Participant interview lasting approximately an hour, donation of a 38ml blood sample and an interview with a Study Partner also lasting around an hour to an hour and a half.
This study is funded by the Medical Research Council. Around 2000 participants from 75 study centres across the UK will take part in this research.REC name
Scotland A: Adults with Incapacity only
REC reference
17/SS/0139
Date of REC Opinion
29 Dec 2017
REC opinion
Favourable Opinion