ALSPAC RTB

• Research type

  Research Tissue Bank

• IRAS ID

  301701

• Research summary

  Avon Longitudinal Study of Parents and Children (ALSPAC) Research Tissue Bank

• REC name

  South West - Central Bristol Research Ethics Committee

• REC reference

  23/SW/0058

• Date of REC Opinion

  2 Jun 2023

• REC opinion

  Favourable Opinion

• Data collection arrangements

  Samples within the RTB are collected from participants of the Avon Longitudinal Study of Parents and Children (ALSPAC), also know as Children of the 90s. ALSPAC is a birth cohort that recruited >14000 pregnant women in the Avon area between April 1991 and December 1992. Mothers, fathers, children and now children of the children from this recruitment have been followed up at multiple timepoints and a wide variety of samples, exposure and outcome measures collected.

  Over 1.5 million biological samples have been collected from participants throughout the lifecourse of the study and are stored in line with the consent in which they were given. The RTB is managed by the Bristol Bioresource Laboratories who provide a high quality professional and responsive sample processing and biobanking service based at the University of Bristol.

• Research programme

  Samples from ALSPAC participants are available to the scientific research community, following the relevant approvals. ALSPAC provides a unique opportunity to study how socioeconomic, lifestyle, patho-physiological, metabolic, genomic and epigenomic factors influence health and wellbeing. ALSPAC is the only human study to be able to do this with relevant detailed data and samples across all major life events.

• Storage license

  12512

• RTBTitle

  Avon Longitudinal Study of Parents and Children (ALSPAC) Research Tissue Bank

• Establishment organisation

  University of Bristol

• Establishment organisation address

  Beacon House

  Queens Road

  Bristol

  BS8 1QU