Aetiopathogenesis of female genital lichen sclerosus
Research type
Research Study
Full title
Aetiopathogenesis of female genital lichen sclerosus
IRAS ID
259858
Contact name
Christopher B Bunker
Contact email
Sponsor organisation
University College London
Clinicaltrials.gov Identifier
Z6364106/2020/02/108, UCL data protection
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Lichen sclerosus is an inflammatory skin condition that can affect the skin on any part of the body, but most often affects the genital skin. It can affect males and females of any age, and the cause is unknown. The most common symptom of genital lichen sclerosus is itching. It may be sore, especially if the skin cracks. In the genital area, the scar-like process that results can affect the skin’s flexibility, and affect urination and sexual intercourse. There is an association with genital cancer.
This research is being undertaken to help clarify the cause of female genital lichen sclerosus (FGLSc) by establishing whether the bacteria or fungi present in urine, on or the vulval skin plays a role in causing genital lichen sclerosus. We are looking at many different individuals with and without this skin disease and hope to find out why some individuals are affected by this skin condition and not others.REC name
Yorkshire & The Humber - South Yorkshire Research Ethics Committee
REC reference
21/YH/0114
Date of REC Opinion
23 Aug 2021
REC opinion
Further Information Favourable Opinion