Adolescent TB in London

  • Research type

    Research Study

  • Full title

    Adolescents and young adults with TB in North-West London: observational cohort study and qualitative analysis

  • IRAS ID

    295032

  • Contact name

    Elizabeth A Whittaker

  • Contact email

    e.whittaker@imperial.ac.uk

  • Sponsor organisation

    Research Governance and Integrity Team (RGIT)

  • Duration of Study in the UK

    2 years, 3 months, 1 days

  • Research summary

    Tuberculosis (TB) in the UK is not very common, but 35% of all TB cases in the UK are present in London. In 2019 there were 1665 new cases of TB reported. That makes London the TB capital in Europe. We know that TB disease tends to progress the fastest in adolescents and young adults, but it is not clear what causes the disease to progress. Some scientists believe that the hormones or viruses might play some role, as well as issues faced by young people like poor adherence, disengagement with the TB services and stigmatisation.
    We will investigate whether TB progression is linked to these factors. We will also explore the impact of TB on the physical, mental and social wellbeing of young people aged 10 to 24 years.We will compare the data gathered from young people with active TB and to those with latent TB and health controls. We hope that the data gathered in this study will help us understand TB in young people better and allow us to create a first in Europe TB clinic tailored specifically to the needs of adolescents and young adults.

  • REC name

    Wales REC 7

  • REC reference

    22/WA/0221

  • Date of REC Opinion

    11 Oct 2022

  • REC opinion

    Further Information Favourable Opinion