ADJUNCTIVE GP ABLATION IN REDO-PVI STUDY (ADD-GP)
Research type
Research Study
Full title
ADJUNCTIVE GP ABLATION IN REDO-PVI STUDY (ADD-GP): PAROXYSMAL ATRIAL ARRHYTHMIAS AFTER PULMONARY VEIN ISOLATION ARE DRIVEN BY ECTOPY-TRIGGERING LEFT ATRIAL GANGLIONATED PLEXI
IRAS ID
218759
Contact name
Becky Ward
Contact email
Sponsor organisation
Imperial College London
Duration of Study in the UK
3 years, 0 months, 0 days
Research summary
Atrial fibrillation (AF) is the most common rhythm disturbance of the heart. It can affect people in their 30s but more and more people have it as they get older. It can cause palpitations, breathlessness, lethargy and even fainting attacks. The most effective treatment for it involves burning or freezing the heart muscle in a chamber of the heart called the left atrium. This is usually directed at the muscle around the veins that drain blood from the lungs back into the heart and the procedure is called a 'pulmonary vein isolation'. The same tissue injury is performed in all patients and it has a success rate of about 60% for preventing AF. We believe that we have developed a more targetted treatment that only injures the muscle around the nerves that trigger atrial fibrillation. We have an ongoing study that confirms our method works. In this new study we would like to find out when the standard procedure has not worked, is it better to do it again, as is customary or to target the triggering nerves (GP sites) as well
REC name
London - Fulham Research Ethics Committee
REC reference
17/LO/0465
Date of REC Opinion
30 Mar 2017
REC opinion
Favourable Opinion