ADC as a Prognostic Biomarker in Cervical Cancer

• Research type

  Research Study

• Full title

  Diffusion-Weighted MRI at 3T using an Endovaginal Coil: Evaluating the Prognostic Value of the Apparent Diffusion Coefficient Distribution in Stage 1 Cervical Tumours.

• IRAS ID

  104175

• Contact name

  Nandita deSouza

• Contact email

  Nandita.desouza@icr.ac.uk

• Sponsor organisation

  The Institute of Cancer Research

• Research summary

  This study aims to develop the technique of Diffusion-Weighted Magnetic Resonance Imaging (DW-MRI)for the assessment of stage 1 cervical cancers. An endovaginal receiver coil has been designed and developed at the Institute of Cancer Research and Royal Marsden NHS Foundation Trust for use at high field strengths (3T). This will be used to evaluate if DW-MRI at 3T can be used to differentiate different histological characteristics within whole tumours and so determine if the technique could be of prognostic value.

• REC name

  East of England - Cambridge East Research Ethics Committee

• REC reference

  13/EE/0198

• Date of REC Opinion

  22 Aug 2013

• REC opinion

  Further Information Favourable Opinion