ADAPT Aspirin Dose Accuracy in PaediaTrics
Research type
Research Study
Full title
Aspirin tablets: Impact of Human factors on manipulation and dosing accuracy in a paediatric healthcare population
IRAS ID
241185
Contact name
Hannah Batchelor
Contact email
Duration of Study in the UK
0 years, 5 months, 30 days
Research summary
Adult pharmaceutical products are frequently given to children, and pharmacists or nurses are required to manipulate these for the patient to take the appropriate dose.
The need for an age-appropriate aspirin formulation had been previously identified based on the need of accurate dosing and poor palatability of crushed tablets.
This study will:
(i) Seek to explore common instructions provided to pharmacists and nurses on how to prepare the requested aspirin dose for children from a 75mg tablet.
(ii) Measure the accuracy of the aspirin dose via analysis of the aspirin content of the manipulated dose prepared by a variety of pharmacists and nurses.
The results will be used to provide advice on appropriate manipulation and potentially to justify the use of an alternative age-appropriate dosage form for children to ensure children get the medication they need.
This study will not involve any patients and all manipulations will be undertaken by healthcare professionals for analysis in the laboratory. None of these doses will be administered to children.REC name
N/A
REC reference
N/A