Acute Exercise & Appetite Regulation in Lean vs. Obese: INTAKE
Research type
Research Study
Full title
The acute effects of exercise on appetite regulatory hormones, appetite perceptions and ad libitum energy intake in lean vs. obese men and women.
IRAS ID
124117
Contact name
Melanie Davies
Contact email
Sponsor organisation
University of Leicester
Research summary
Body weight is determined by energy balance, the difference between energy intake and energy expenditure. To lose weight it is necessary to make this negative by either decreasing calorie consumption or increasing energy expenditure. Reducing energy intake is often seen to be unattractive and therefore recent research has examined the effect of increasing energy expenditure through exercise. The effect that this has on appetite determines its effectiveness for weight loss and maintenance of body weight.
In lean, healthy individuals it has been shown that following an acute bout of exercise appetite is temporarily reduced and individuals are more sensitive at matching their energy intake with energy expenditure. It would appear that this is related to gut hormones found within the blood that regulate appetite control and energy balance. Obese individuals have been shown to display a dysfunction in this appetite regulatory system. This means that following a meal these individuals are less satisfied and show a higher desire to consume food. The proposed investigation seeks to determine whether the beneficial effects of exercise on appetite control seen in lean individuals translate into the obese.
The aim of this investigation is to determine the effect of a single bout of exercise on appetite regulatory hormones, appetite perceptions and ad libitum energy intake in lean vs. obese men and women. To accomplish this we will collect blood samples, appetite questionnaire responses and measure energy intake from a buffet meal in both normal weight (16 females and 16 males) and obese (16 females and 16 males) individuals aged between 18 and 50 years.
This research will improve knowledge about the impact of exercise on appetite regulation and energy balance. In particular, it will determine whether previously reported favorable effects translate into real benefits in a population who suffer from impaired appetite regulation.
REC name
East Midlands - Nottingham 1 Research Ethics Committee
REC reference
13/EM/0290
Date of REC Opinion
7 Oct 2013
REC opinion
Further Information Favourable Opinion