ACED Cohort
Research type
Research Study
Full title
Alliance for Cancer Early Detection (ACED)Cohort
IRAS ID
282474
Contact name
Rebecca Fitzgerald
Contact email
Sponsor organisation
Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
Clinicaltrials.gov Identifier
12315, HTA License Number ; GBR-1-302, UKCRC- Tissue Directory; HVS/2020/3071, Insurance Reference
Duration of Study in the UK
3 years, 5 months, 1 days
Research summary
This project aims to provide baseline and longitudinal information on patients attending the Early Detection research clinic which tests new approaches for identification of individuals at high risk for cancer. When patients attend this clinic we plan to collect demographic, physiological and epidemiological information, and store biological samples (e.g. DNA, blood, blood derivatives and urine) from a minimum of 200 adults per year. Many of these individuals will be volunteers and this cohort will be valuable for researchers to establish biomarker thresholds for healthy individuals. This cohort will also allow us to better understand risk factors for cancer and explore techniques and methodologies to detect cancer at an earlier stage. Participants will be consented so that we maintain a population cohort enriched for risks of specific cancers and track disease outcomes. These participants may also be invited for further studies and longitudinal sampling with the aim that these participants and/or samples can be accessed for other genetic biomedical studies and clinical trials including first in humans.
REC name
East of England - Cambridge South Research Ethics Committee
REC reference
20/EE/0273
Date of REC Opinion
11 Dec 2020
REC opinion
Unfavourable Opinion