AAV Antibodies in UK cohort of Haemophilia A Patients

• Research type

  Research Study

• Full title

  Adenovirus-Associated Antibodies in UK cohort of Haemophilia A Patients: A seroprevalence study of the presence of Adenovirus-Associated Virus Vector–serotypes AAV2, AAV5 and AAV8 neutralizing activity and antibodies in Patients with Haemophilia A

• IRAS ID

  179874

• Contact name

  Savita Rangarajan

• Contact email

  savita.rangarajan@hhft.nhs.uk

• Sponsor organisation

  Hampshire Hospitals NHS Foundation Trust

• Duration of Study in the UK

  1 years, 0 months, 1 days

• Research summary

  This is an observational laboratory cohort study to determine the seroprevalence of AAV neutralizing factors and antibodies in haemophilia A patients previously treated with FVIII concentrate.

• REC name

  North West - Liverpool Central Research Ethics Committee

• REC reference

  15/NW/0469

• Date of REC Opinion

  27 May 2015

• REC opinion

  Favourable Opinion