A Study to Investigate Concentrations of ALB-127158 in Plasma and CSF

• Research type

  Research Study

• Full title

  A Pharmacokinetic Study to Investigate the Concentrations of ALB 127158 in Plasma and Cerebral Spinal Fluid in Healthy Male Subjects Following a Single Oral Dose of ALB-127158(a)

• IRAS ID

  82233

• Contact name

  Joseph Chiesa

• Sponsor organisation

  Albany Molecular Research Inc

• Research summary

  Single oral dose study in healthy male subjects to assess the distribution of ALB-127158(a) into cerebrospinaflud (CSF). 9 subjects will be studied as a single group. Subjects will participate in a single treatment period, residing at the Clinical Research Unit (CRU) from Day ??1 (the day before dosing) to Day 3 (48 hours postdose).

• REC name

  East of England - Cambridgeshire and Hertfordshire Research Ethics Committee

• REC reference

  11/IE/0094

• Date of REC Opinion

  1 Nov 2011

• REC opinion

  Further Information Favourable Opinion