A study on the incidence of persistent pain and fatigue post COVID-19

• Research type

  Research Study

• Full title

  A STUDY ON THE INCIDENCE OF OF PERSISTENT PAIN AND FATIGUE FOLLOWING INFECTION WITH THE COVID-19 VIRUS IN TWO COHORTS: 1. PARTICIPANTS WHO WERE UNWELL ENOUGH TO REQUIRE ADMISSION TO HOSPITAL WITH ACUTE COVID-19 INFECTION 2. PARTICIPANTS WHO WERE INFECTED WITH COVID BUT DID NOT REQUIRE ADMISSION TO HOSPITAL

• IRAS ID

  287475

• Contact name

  Lorraine Evelyn de Gray

• Contact email

  lorraine.degray@qehkl.nhs.uk

• Sponsor organisation

  The Queen Elizabeth Hospital NHS Foundation Trust

• Duration of Study in the UK

  0 years, 3 months, 31 days

• Research summary

  COVID -19 infection in the acute phase can present with many symptoms including pain and fatigue. Ear pain, chest pain, joint pains, muscle pain and fatigue are common symptoms during the acute phase of infection. Abdominal pain or discomfort has been reported in 2.2 to 5.8% of patients in the acute phase. Headaches are also reported either in their own right or less commonly as a manifestation of neurological complications arising from the viral infection. Less common manifestations include testicular pain, more focal muscle pain secondary to rhabdomyolysis and painful vasculitic lesions affecting the extremities. Severe fatigue is also being reported by many in the acute phase.
  As the pandemic evolves, it is becoming increasingly evident that several patients are continuing to suffer from long term sequelae of the infection. There is increasing evidence to suggest that the more severe the illness, the higher is the likelihood of long- term repercussions, with impaired respiratory function, cardiac dysfunction and new onset diabetes being described up to now. Anecdotally, many patients continue to report significant pain and fatigue weeks after being diagnosed or showing symptoms of acute COVID 19 infection. Whether chronic long term pain and fatigue will become one of these sequelae remains yet to be seen. This study aims to look at the incidence of persistent pain and fatigue in two groups of participants, namely ones that were ill enough to require admission and the second group who were managed at home.

• REC name

  Yorkshire & The Humber - Sheffield Research Ethics Committee

• REC reference

  20/YH/0321

• Date of REC Opinion

  26 Nov 2020

• REC opinion

  Favourable Opinion