A Register for New Anti-Epileptic Drugs In ID/PDD populations

  • Research type

    Research Database

  • IRAS ID

    160521

  • Contact name

    Jon Allard

  • Contact email

    jon.allard@nhs.net

  • Research summary

    A register for collecting and measuring outcomes of licensed Anti-Epileptic drugs (AEDs) in patients with Epilepsy and Intellectual Disability (ID) and/or Pervasive Developmental Disorders(PDD)

  • REC name

    South Central - Oxford C Research Ethics Committee

  • REC reference

    14/SC/1270

  • Date of REC Opinion

    29 Oct 2014

  • REC opinion

    Further Information Favourable Opinion

  • Data collection arrangements

    Data will be collected using RIO by the
    researcher. The data will be made up of 17 parameters and stored on an excel spreadsheet which will be encrypted
    and password protected.
    The parameters are to include the following: age, sex, type of ID (mild/moderate/severe/profound/unavailable), ID data
    (from casenotes/
    IQ test), details of pervasive development disorder (such as autism), chronic medical condition
    (nature of and diagnosis), seizure type (generalized, complex partial, partial), seizure frequency, seizure intensity, age
    of onset (first seizure), AED medication, midazolam/diazepan (for rescue), QOL score (radar score/impact scale).
    Research programme/community supported by the database

  • Research programme

    This project would help identify and clarify the role of newer AEDs in patients with ID/PDD. Given the lack of available clinical evidence in this area it is paramount that this research happens. It would benefit all patients with epilepsy and AED. It would increase scientific awareness in AED prescribing.

  • Research database title

    A register for collecting and measuring outcomes of licensed Anti-Epileptic drugs (AEDs) in patients with Epilepsy and Intellectual Disability (ID) and/or Pervasive Developmental Disorders(PDD)

  • Establishment organisation

    Cornwall Partnership NHS Foundation Trust

  • Establishment organisation address

    Trengweath

    Penryn Street

    Redruth

    TR15 2SP