A Phase 1/2 Study of INCB099280 in Combination With Axitinib in Adults With Advanced Solid Tumors

  • Research type

    Research Study

  • Full title

    A Phase 1/2 Study of INCB099280 in Combination With Axitinib in Adults With Advanced Solid Tumors

  • IRAS ID

    1008251

  • Contact name

    Carol Penning

  • Contact email

    cpenning@incyte.com

  • Sponsor organisation

    Incyte Corporation

  • Eudract number

    2022-003663-13

  • Research summary

    The study is looking at whether axitinib can be safely given with INCB099280 (an agent that helps the immune system identify and fight cancer cells ) and if this may result in better clinical outcomes in adults with previously treated advanced clear-cell or rare histological subtype epithelial gynecological cancers who are not able to have curative surgery or (chemo)radiation.

  • REC name

    London - City & East Research Ethics Committee

  • REC reference

    23/LO/0762

  • Date of REC Opinion

    13 Oct 2023

  • REC opinion

    Further Information Favourable Opinion