Research summaries

Last updated: 25 Nov 2024

Our research summaries pages have information about every research study that is reviewed by a Research Ethics Committee (REC) in the UK. The information in these research summaries is extracted from the IRAS application form. Further information about the research can be obtained from the contact details listed in the research summary.

Sponsors may request the deferral of the publication of the research summary where there are concerns of commercial confidentiality. The sponsor/researcher/applicant can also request updates to the information published in the research summary.

61019 records for COVID

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Bioequivalence of TK-641 vs Oxycontin® in a fed state Version 1
- 28 Oct 2008
- Research Study
- REC reference: 08/H0717/60
- IRAS ID: 7950
Japanese pharmaceutical company who has a license of controlled drug which is being developed by a company in Europe would …
Switch of Darbeopetin to AF37702 Injection in Haemodialysis Patients
- 28 Oct 2008
- Research Study
- REC reference: 08/S0501/70
- IRAS ID: 5661
Anaemia occurs when there isnot enough haemoglobin in the blood. Haemoglobin gives red blood cells theircolour and is responsible for …
Clofarabine Used with DaunoXome in Childhood AML - CLOUD Trial
- 28 Oct 2008
- Research Study
- REC reference: 08/H1208/36
- IRAS ID: 3909
Approximately 35% of children and adolescents with acute myeloid leukaemia are not cured with current therapies. New drugs or drug …
MK-0646 plus Erlotinib in Recurrent Non-Small Cell Lung Cancer
- 28 Oct 2008
- Research Study
- REC reference: 08/H0904/90
Effect of statins on functional regulation of eNOS in heart failure.
- 28 Oct 2008
- Research Study
- REC reference: 08/NIR01/74
Statins are drugs which lower cholesterol and reduce the risk of cardiovascular events such as heart attack and stroke, and …
Aliskiren & amlodopine combination treatment for hypertension v1.0
- 28 Oct 2008
- Research Study
- REC reference: 08/H0502/131
- IRAS ID: 7911
COMParing the efficacy sAfety & toleRability of paZopanib vs sunitinib
- 28 Oct 2008
- Research Study
- REC reference: 08/H1010/70
- IRAS ID: 3788
Research Summary This is a randomized, open label, Phase III study to evaluate the efficacy and safety of pazopanib compared …
Is Hedrin 4% effective in 1 hour?
- 27 Oct 2008
- Research Study
- REC reference: 08/H0301/114
Hedrin 4% lotion has demonstrated efficacy in two randomised, controlled, comparative trials. The current treatment regimen is two applications for …
Protocol No FPP4-DE-401 Penciclovir 1% Cream Efficacy Study
- 27 Oct 2008
- Research Study
- REC reference: 08/NIR02/90
The primary objective of this trial is to compare how effective penciclovir (1%) cream is in preventing the development of …
Sperm suppression and contraceptive provided by NET-EN & TU
- 24 Oct 2008
- Research Study
- REC reference: 08/H1008/121
This study is important as a long standing goal of the WHO/RHR and CONRAD is to develop a safe, effective …
Phase III Ritonavir-Boosted Elvitegravir Vs. Raltegravir HIV Study
- 24 Oct 2008
- Research Study
- REC reference: 08/H0405/40
- IRAS ID: 3510
The Human Immunodeficiency Virus (HIV) attacks the immune system, which protects the body against disease and infection. HIV infection can …
Efficacy and Safety of Romiplostim Treatment of Thrombocytopenia
- 24 Oct 2008
- Research Study
- REC reference: 08/H1307/108
- IRAS ID: 4706
Myelodysplastic syndromes (MDS) are a group of diseases in which the production of blood cells by the bone marrow is …
Safety,Efficacy,Tolerability Study of 2PX in Chronic Stump Pain
- 24 Oct 2008
- Research Study
- REC reference: 08/H1008/135
- IRAS ID: 6552
This trial will be conducted as a multi-centre, randomised, double-blind, parallel-group study, in patients with chronic, moderate to severe lower …
Nilotinib Therapy After Reduced Intensity Conditioned Transplantation
- 24 Oct 2008
- Research Study
- REC reference: 08/H0304/91
- IRAS ID: 6270
Allogeneic stem celltransplantation is one of the only curative treatment options for many patientswith Chronic Myeloid Leukaemia (CML). However, it …
Phase I study to assess pharmacokinetics of a candidate microbicide
- 23 Oct 2008
- Research Study
- REC reference: 08/H0304/87
Vaginal microbicides are being developed as products to prevent HIV transmission. These products are designed to be applied intravaginally prior …
Contrast enhanced ultrasound to detect intraplaque neovascularisation
- 23 Oct 2008
- Research Study
- REC reference: 08/H0706/106
- IRAS ID: 3620
Atherosclerotic plaques grow within the walls of arteries. The majority of plaques do not cause symptoms, but some can suddenly …
Effect of chemotherapy on atherosclerotic plaque neovascularisation
- 23 Oct 2008
- Research Study
- REC reference: 08/H0720/124
- IRAS ID: 2960
Atherosclerotic plaques grow within the walls of arteries. Plaques can be asymptomatic, grow slowly, or can suddenly rupture. Most heart …
RT3 VIN
- 23 Oct 2008
- Research Study
- REC reference: 08/NIR03/82
- IRAS ID: 1
VIN is a skin condition affecting the vulval skin which, if untreated, may become cancerous. Symptoms include itching, burning, soreness …
Atomoxetine-HSEN
- 22 Oct 2008
- Research Study
- REC reference: 08/H1102/86
- IRAS ID: 4104
We will conduct a Prospective,open-label trial of atomoxetine in children with learning disabilities (LD) andAttention Deficit Hyperactivity Disorder (ADHD). The …
Knee Osteoarthritis AS902330 First in Man,Proof of Concept,SAD & MAD
- 22 Oct 2008
- Research Study
- REC reference: 08/H0605/107
- IRAS ID: 1884
Osteoarthritis is the most common form of joint disease and one of the most frequent morbidities in the elderly. According …