1-DAY ACUVUE® Moist Multifocal Real World Through Focus Curve
Research type
Research Study
Full title
1-DAY ACUVUE® Moist Multifocal Real World Through Focus Curve
IRAS ID
179643
Contact name
Michel Guillon
Contact email
Sponsor organisation
Johnson & Johnson Vision Care Inc.
Duration of Study in the UK
0 years, 2 months, 11 days
Research summary
The visual acceptance of a multifocal contact lens depends upon the visual performance achieved at the various distances of interest from far to near. The most precise means to quantify the visual performance is the determination of the through focus curve (TFC). The TFC is the measurement of visual acuity at specified distances covering visual acuity from long distance vision (e.g. driving, watching live sports, etc.) to intermediate (e.g. computer screens) and near (e.g. reading). As for all visual acuity measurements the TFC is dependent on contrast and light level (luminance). For multifocal contact lenses the more important of the two factors is luminance since this affects the size of the pupil.
Traditionally TFC measurement is obtained by using drops to dilate the pupil and then using artificial pupils in a trial frame to represent daytime (pupil diameter = 3mm), indoor (pupil diameter = 4.5mm) and night time driving (pupil diameter = 6mm) vision conditions. The various optical distances of interest are then reproduced by testing vision with a chart at optical infinity and adding negative spherical vergence lenses to mimic the near vision demands (e.g. -1.00D mimics 100cm). The drawbacks to this system are that testing is somewhat invasive and can be difficult to implement with the need to very precisely centre both the vergence lenses and the artificial pupils. In addition, the use of vergence lenses does not represent the true “real world” environment.
The purpose of this study will be to establish a real world TFC for1-DAY ACUVUE® Moist® Multifocal contact lenses by precisely measuring the visual acuity achieved at a range of distances that replicate those used during everyday activities under different lighting levels monocularly (for one eye at a time) and binocularly (for both eyes together).
REC name
West Midlands - South Birmingham Research Ethics Committee
REC reference
15/WM/0158
Date of REC Opinion
21 Apr 2015
REC opinion
Favourable Opinion